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Thursday, July 23, 2020 | History

1 edition of Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol found in the catalog.

Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol

Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol

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Published by Dept. of Health, Education, and Welfare, [Public Health Service], National Institutes of Health in [Bethesda, Md.] .
Written in English

    Subjects:
  • Fertility.,
  • Pregnancy -- Complications.,
  • Diethylstilbestrol -- Side effects.

  • Edition Notes

    StatementAnn B. Barnes ... [et al.].
    ContributionsBarnes, Ann., National Institutes of Health (U.S.).
    The Physical Object
    Paginationp. 609-613 ;
    Number of Pages613
    ID Numbers
    Open LibraryOL17650997M

    Conservative management and pregnancy outcome in diethylstilbestrol-exposed women with and without gross genital tract abnormalities. Am J Obstet Gynecol ; Wise LA, Palmer JR, Hatch EE, et al. Secondary sex ratio among women exposed to diethylstilbestrol in utero.   Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol. Impaired reproductive performance in DES-exposed women. Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities. DES Effect on Males.

    Adverse outcomes of pregnancy in women exposed to diethylstilbestrol in utero. J Reprod Med ;33(1) Mangan CE, Borow L, Burtnett-Rubin MM, Egan V, Giuntoli RL, Mikuta JJ. Pregnancy outcome in 98 women exposed to diethylstilbestrol in utero, their mothers, and unexposed siblings. Obstet Gynecol ; Muasher SJ, Garcia JE, Jones HW. Barnes AB, Colton T, Gundersen J, et al: Fertility and the outcome of pregnancy in women exposed in utero to diethylstilbestrol. N Engl J Med –, PubMed CrossRef Google Scholar Author: David F. Archer.

      Genital tract abnormalities and adverse pregnancy outcome are well known in women exposed in utero to diethylstilboestrol (DES). Data about adverse reproductive performance in women exposed to DES have been published, including controversial reports of menstrual dysfunction, poor responses after ovarian stimulation, oocyte maturation and fertilization by: Adverse Outcomes in Women Exposed to Diethylstilbestrol n engl j med ;14 october 6, S oon after the first synthetic estro-gen, diethylstilbestrol (DES), was developed in ,1 it was used clinically to prevent complications of pregnancy.2 In the early s, four clinical trials revealed no evidence of efficacy.


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Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol Download PDF EPUB FB2

Original Article from The New England Journal of Medicine — Fertility and Outcome of Pregnancy in Women Exposed in Utero to Diethylstilbestrol logo logoCited by:   Fertility and outcome of pregnancy were examined in women participating in the National Cooperative Diethylstilbestrol Adenosis (DESAD) Project.

We compared subjects who had prenatal exposure to DES with control subjects. Fertility, measured in terms of pregnancies achieved, did not differ between the women exposed to DES and the by:   Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol.

N Engl J Med. Mar 13; (11)– Henderson BE, Benton B, Cosgrove M, Baptista J, Aldrich J, Townsend D, Hart W, Mack TM. Urogenital tract abnormalities in sons of women treated with diethylstilbestrol. Pediatrics. Oct; 58 (4)–Cited by: 2. Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol, The New England journal of medicine, NCBI PubMed PMID:Mar Fertility and outcome of pregnancy were examined in women participating in the National Cooperative Diethylstilbestrol Adenosis (DESAD) Project.

PIP Current knowledge regarding the pregnancy outcome for women exposed to DES (diethylstilbestrol) in utero is presented using information from a. Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol.

N Engl J Med. Mar 13; (11)– Bibbo M, Haenszel WM, Wied GL, Hubby M, Herbst AL. A twenty-five-year follow-up study of women exposed to diethylstilbestrol during pregnancy. N Engl J Med. Apr 6; (14)–Author: Michael Malus, Alex Ferenczy. The presence of anomalies in vagina, cervix, and uterine body of women exposed to diethylstilbestrol in utero has provoked interest and concern regarding the reproductive potential of these women.

To expand and to evaluate better better the current knowledge in this matter, the outcomes of the pregnancies of exposed women registered in the Stilbestrol Clinic at the Stanford.

In utero exposure of women to DES is associated with a high lifetime risk of a broad spectrum of adverse health outcomes. Abstract. Adverse health outcomes in women exposed in utero to diethylstilbestrol, The New England journal of medicine, NCBI PubMed PMID:Oct.

Full text: NEJM, DOI: /NEJMoa, October 6, BACKGROUND. Purpose: The outcome of in vitro fertilization (IVF) in a group of infertile women with a history of in utero exposure to diethylstilbestrol (DES) was analyzed. Records from an academic IVF program were retrospectively reviewed. Methods: Seventeen infertile women with a self-reported history of exposure to DES in utero, Cited by: 9.

Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol. Impaired reproductive performance in DES-exposed women. Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities. Barnes AB, Colton T, Gundersen J, et al.

Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol. N Engl J Med ; Full Text; Web of Science; Medline Cited by: Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol.

[Bethesda, Md.]: Dept. of Health, Education, and Welfare [Public Health Service], National Institutes of Health, (OCoLC) Material Type: Government publication, National government publication: Document Type: Book: All Authors / Contributors. Assisted reproductive technology Are implantation and pregnancy outcome impaired in diethylstilbestrol-exposed women after in vitro fertilization and embryo transfer?* * Presented in part at the 38th Annual Meeting of The American College of Obstetricians and Gynecologists, San Francisco, California, May 7 to 10, Cited by: The chapter gives an overview of medical drugs impairing fertility in men and women.

Drugs may impair male fertility by interfering with spermatogenesis, sperm motility, or by interfering with the fertilising capacity of spermatozoa. Female fertility may be compromised by impairing oogenesis, ovulation, or through the suppression of ovarian Cited by: 4. Diethylstilbestrol (DES) is a synthetic form of the female hormone was prescribed to pregnant women between and to prevent miscarriage, premature labor, and related complications of pregnancy ().The use of DES declined after studies in the s showed that it was not effective in preventing these problems.

Fertility and outcome of pregnancy were examined in women participating in the National Cooperative Diethylstilbestrol Adenosis (DESAD) Project.

We compared subjects who had prenatal exposure. R.H. Kaufman, E. Adam, G.L. Binder, E. Gerthoffer, Upper genital tract changes and pregnancy outcome in offspring exposed in utero to diethylstilbestrol Am J Obstet Gynecol () G.

Schmidt, W.C. Fowler, Cervical stenosis following minor gynecologic procedures on DES-exposed women Obstet Gynecol () Cited by: These data suggest that in utero exposure to DES results in permanent impairment of female mouse reproductive capacity.

Recent reports of altered pregnancy outcomes in young women who were exposed in utero to DES demonstrate the clinical importance of the findings obtained in mice. REFERENCES by: Scientific Articles Experience with diethylstilbestrol-exposed infertile women in a program of in vitro fertilization Suheil J.

Muasher, M.D. * Jairo E. Garcia, M.D. Howard W. Jones, Jr. M.D. Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia Department of Obstetrics and Gynecology, Eastern Virginia Medical School Norfolk Virginia * Reprint requests Cited by: In addition, researchers found that the timing of DES exposure in the womb (the trimester (s) during which exposure to DES took place) had some effect on infertility rates.

Specifically, 24% of DES Daughters had never become pregnant compared with 18% of unexposed women. Most DES Daughters who never became pregnant had been exposed to DES.

Diethylstilbestrol (DES) is a polycyclic nonsteroidal estrogen that readily crosses the placenta and has been shown, in animal studies, to concentrate in the urogenital tract of the developing fetus (1, 2, 3).Worldwide, between 1 and 4 million men and women were exposed prenatally to DES from about through the s ().Numerous studies have shown that women who were exposed to DES Cited by: Outcome of pregnancy in patients exposed in utero to diethylstilbestrol.

Survey by the National College of French Gynecologists and Obstetricians. Pregnancy after gamete intrafallopian transfer in a woman with primary infertility and in utero exposure to diethylstilbestrol.Barnes, A.

B., Colton, T., Gunderson et al. (). Fertility and outcome of pregnancy in women exposed in utero to diethylstilbestrol.

N. Engl. J. Med.,Cited by: 1.